Frontiers in immunology

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1. 2025

   • Vol. 16: Worse recovery from acute attacks and faster disability accumulation highlights the unmet need for improved treatment in patients with late-onset neuromyelitis optica spectrum disorders (COPTER-LO study)

     Kretschmer, Julian Reza; Tkachenko, Daria; Kümpfel, Tania; Havla, Joachim; Engels, Daniel; Paul, Friedemann; Schindler, Patrick; Bellmann-Strobl, Judith; Berthele, Achim; Giglhuber, Katrin; Zappe, Clarissa; Klotz, Luisa; Revie, Lisa; Dawin, Eva; Şenel, Makbule; Tumani, Hayrettin; Then Bergh, Florian; Warnke, Clemens; Kraemer, Markus; Walter, Annette; Bayas, Antonios; Zettl, Uwe K.; Lauenstein, Ann-Sophie; Yalachkov, Yavor; Etgen, Thorleif; Kaste, Matthias; Lüssi, Felix; Gingele, Stefan; Passoke, Sarah; Weber, Martin S; Sieb, Jörn Peter; Haarmann, Axel; Oschmann, Patrick; Rothhammer, Veit; Geis, Christian; Kowarik, Markus C.; Kern, Peter; Grothe, Matthias; Stephanik, Heike; Angstwurm, Klemens; Hoffmann, Frank; Wallwitz, Ulrike; Wildemann, Brigitte; Jarius, Sven; Stellmann, Jan-Patrick; Pakeerathan, Thivya; Schwake, Carolin; Ayzenberg, Ilya; Kleiter, Ingo; Fischer, Katinka; Aktas, Orhan; Ringelstein, Marius; Häußler, Vivien; Trebst, Corinna; Hümmert, Martin W

   • Vol. 16: Reappraisal of IgG subclass deficiencies : a retrospective comparative cohort study

     Dogru, Damla; Dogru, Yagmur; Atschekzei, Faranaz; Elsayed, Abdulwahab; Dubrowinskaja, Natalia; Ernst, Diana; Witte, Torsten; Gödecke, Vega; Sogkas, Georgios

   • Vol. 16: PET imaging of tissue reactions in the implanted cochlea: results of a pilot study

     Deutsch, Philipp; Bankstahl, Jens P.; Mamach, Martin; Willmann, Michael; Bengel, Frank M.; Lenarz, Thomas; Berding, Georg; Scheper, Verena; Schwieger, Jana

   • Vol. 16: In vivo RNAi screen and validation reveals Ngp, Hba-a1, and S100a8 as novel inhibitory targets on T lymphocytes in liver cancer

     Hochnadel, Inga; Hoenicke, Lisa; Petriv, Nataliia; Suo, Huizhen; Groebe, Lothar; Olijnik, Chantal; Bondarenko, Nina; Alfonso, Juan C; Jarek, Michael; Shi, Ruibing; Jeron, Andreas; Timrott, Kai; Hirsch, Tatjana; Jedicke, Nils; Bruder, Dunja; Klawonn, Frank; Lichtinghagen, Ralf; Geffers, Robert; Lenzen, Henrike; Manns, Michael P; Yevsa, Tetyana

   • Vol. 16: Idiopathic inflammatory myopathy associated with Sjögren’s disease : features of a distinct clinical entity

     Konen, Franz Felix; Güzeloglu, Yunus Emre; Seeliger, Dr. Tabea; Jendretzky, Konstantin Fritz; Nay, Sandra; Grote-Levi, Lea; Schwenkenbecher, Philipp; Gründges, Christine; Ernst, Diana; Witte, Torsten; Skripuletz, Thomas

   • Vol. 16: Identification of novel autoantibodies in Sjögren's disease

     Engelke, Fiona; Budde, Petra; De Vita, Salvatore; Dörner, Thomas; Ernst, Diana; Gras, Jan; Heidecke, Harald; Kilian, Annika Loredana; Kniesch, Katja; Lindemann, Ann-Sophie; Quartuccio, Luca; Ritter, Jacob; Schulze-Forster, Kai; Seeliger, Benjamin; Zucht, Hans-Dieter; Witte, Torsten

   • Vol. 16: Acquisition of innate B cell properties and generation of autoreactive IgA antibodies by follicular B cells during homeostatic proliferation

     Kampe, Laura; Melcher, Christian; Westphal, Katrin; Brand, Korbinian; Föger, Niko; Lee, Kyeong-Hee

   • Vol. 16: Ablation of the deubiquitinating enzyme cylindromatosis (CYLD) augments STAT1-mediated M1 macrophage polarization and fosters Staphylococcus aureus control

     Schmidt, Christina; Harit, Kunjan; Traidl, Stephan; Naumann, Michael; Werfel, Thomas; Roesner, Lennart M; Nishanth, Gopala; Schlüter, Dirk
2. 2024

   • Vol. 15: Long-term increase in soluble interleukin-6 receptor levels in convalescents after mild COVID-19 infection

     Lokau, Juliane; Garbers, Yvonne; Vicente, Manuel M; Dittrich, Anna; Meltendorf, Stefan; Lingel, Holger; Münster-Kühnel, Anja; Brunner-Weinzierl, Monika; Garbers, Christoph

   • Vol. 15: JAK inhibitors to treat STAT3 gain-of-function : a single-center report and literature review

     Atschekzei, Faranaz; Traidl, Stephan; Carlens, Julia; Schütz, Katharina; von Hardenberg, Sandra; Elsayed, Abdulwahab; Ernst, Diana; Risser, Linus; Thiele, Thea; Graalmann, Theresa; Raab, Juliana; Baumann, Ulrich; Witte, Torsten; Sogkas, Georgios

   • Vol. 15: Human PD-L1 overexpression decreases xenogeneic human T-cell immune responses towards porcine kidneys

     Schmalkuche, Katharina; Rother, Tamina; Besli, Sevval; Schwinzer, Reinhard; Blasczyk, Rainer; Petersen, Björn; Figueiredo, Constanca

   • Vol. 15: Human CFTR deficient iPSC-macrophages reveal impaired functional and transcriptomic response upon Pseudomonas aeruginosa infection

     Rodriguez González, Claudio; Basílio-Queirós, Débora; Neehus, Anna-Lena; Merkert, Sylvia; Tschritter, David; Ünal, Sinem; Hegermann, Jan; Mörgelin, Matthias; Bustamante, Jacinta; Nietert, Manuel; Martin, Ulrich; Tümmler, Burkhard; Munder, Antje; Lachmann, Nico

   • Vol. 15: Histamine and Th2 cytokines independently and synergistically upregulate MMP12 expression in human M2 macrophages

     Pereira da Fonseca, Alice; Traidl, Stephan; Gutzmer, Ralf; Schaper-Gerhardt, Katrin; Werfel, Thomas; Mommert, Susanne

   • Vol. 15: Hemopexin alleviates sterile inflammation in ischemia-reperfusion-induced lung injury

     Nakagiri, Tomoyuki; Köhler, Nadine R.; Janciauskiene, Sabina; Neubert, Lavinia; Knöfel, Ann-Kathrin; Pradhan, Pooja; Ruhparwar, Arjang; Ius, Fabio; Immenschuh, Stephan

   • Vol. 15: Heart immunoengineering by lentiviral vector-mediated genetic modification during normothermic ex vivo perfusion.

     Schmalkuche, Katharina; Rother, Tamina; Burgmann, Jonathan M; Voß, Henrike; Höffler, Klaus; Dogan, Günes; Ruhparwar, Arjang; Schmitto, Jan Dieter; Blasczyk, Rainer; Ferreira de Figueiredo, Constança Sofia

   • Vol. 15: Alpha1-antitrypsin improves survival in murine abdominal sepsis model by decreasing inflammation and sequestration of free heme

     Zemtsovski, Jan D.; Tumpara, Srinu; Schmidt, Sonja; Vijayan, Vijith; Klos, Andreas; Laudeley, Robert; Held, Julia; Immenschuh, Stephan; Wurm, Florian M.; Welte, Tobias; Haller, Hermann; Janciauskiene, Sabina; Shushakova, Nelli
3. 2023

   • Vol. 14: Third SARS-CoV-2 vaccination and breakthrough infections enhance humoral and cellular immunity against variants of concern

     Ruhl, Louisa; Kühne, Jenny F.; Beushausen, Kerstin; Keil, Jana; Christoph, Stella; Sauer, Jasper; Falk, Christine S.

   • Vol. 14: The aging kidney is characterized by tubuloinflammaging, a phenotype associated with MHC-II gene expression

     Sinning, Julius; Funk, Nils David; Sörensen-Zender, Inga; Wulfmeyer, Vera Christine; Liao, Chieh Ming; Haller, Hermann; Hinze, Christian; Schmidt-Ott, Kai Martin; Melk, Anette; Schmitt, Roland

   • Vol. 14: Single cell RNA sequencing reveals distinct clusters of Irf8-expressing pulmonary conventional dendritic cells

     Jirmo, Adan Chari; Grychtol, Ruth Margarethe; Gaedcke, Svenja; Liu, Bin; DeStefano, Stephanie; Happle, Christine; Halle, Olga; Monteiro, Joao T; Habener, Anika; Breiholz, Oliver D; DeLuca, David; Hansen, Gesine

   • Vol. 14: Reinforcement of cell-mediated immunity driven by tumor-associated Epstein-Barr virus (EBV)-specific T cells during targeted B-cell therapy with rituximab.

     Tischer-Zimmermann, Sabine; Bonifacius, Agnes; Santamorena, Maria Michela; Mausberg, Philip; Stoll, Sven; Döring, Marius; Kalinke, Ulrich; Blasczyk, Rainer; Maecker-Kolhoff, Britta; Eiz-Vesper, Britta

   • Vol. 14: Omicron infection-associated T- and B-cell immunity in antigen-naive and triple-COVID-19-vaccinated individuals.

     Barros-Martins, Joana; Hammerschmidt, Swantje I.; Morillas Ramos, Gema; Cossmann, Anne; Hetzel, Laura; Odak, Ivan; Köhler, Miriam; Stankov, Metodi V.; Ritter, Christiane; Friedrichsen, Michaela; Ravens, Inga; Schimrock, Anja; Ristenpart, Jasmin; Janssen, Anika; Willenzon, Stefanie; Bernhardt, Günter; Lichtinghagen, Ralf; Bošnjak, Berislav; Behrens, Georg M. N.; Forster, Reinhold

   • Vol. 14: Natural killer cells- from innate cells to the discovery of adaptability

     Basílio-Queirós, Débora; Mischak-Weissinger, Eva Maria

   • Vol. 14: CSF-1 and Notch signaling cooperate in macrophage instruction and tissue repair during peripheral limb ischemia

     Kapanadze, Tamar; Gamrekelashvili, Jaba; Sablotny, Stefan; Kijas, Dustin; Haller, Hermann; Schmidt-Ott, Kai; Limbourg, Florian P

   • Vol. 14: CD14highCD16+ monocytes are the main producers of Interleukin-10 following clinical heart transplantation.

     Ludwig, Kristina; Chichelnitskiy, Evgeny; Kühne, Jenny F.; Wiegmann, Bettina Pamela; Iske, Jasper; Ledwoch, Nadine; Ius, Fabio; Beushausen, Kerstin; Keil, Jana; Iordanidis, Susanne; Rojas, Sebastian V.; Salman, Jawad; Knöfel, Ann-Kathrin; Haverich, Axel; Warnecke, Gregor; Falk, Christine S

   • Vol. 14: CAR-Ts redirected against the Thomsen-Friedenreich antigen CD176 mediate specific elimination of malignant cells from leukemia and solid tumors.

     Dragon, Anna Christina; Beermann, Luca Marie; Umland, Melina; Bonifacius, Agnes; Malinconico, Chiara; Ruhl, Louisa; Kehler, Patrik; Gellert, Johanna; Weiß, Lisa; Mayer-Hain, Sarah; Zimmermann, Katharina; Riese, Sebastian; Thol, Felicitas; Beutel, Gernot; Maecker-Kolhoff, Britta; Yamamoto, Fumiichiro; Blasczyk, Rainer; Schambach, Axel; Hust, Michael; Hudecek, Michael; Eiz-Vesper, Britta

   • Vol. 14: Association of torque teno virus viremia with liver fibrosis in the first year after liver transplantation.

     Engel, Bastian; Görzer, Irene; Campos-Murguia, Alejandro; Hartleben, Björn; Puchhammer-Stöckl, Elisabeth; Jäckel, Elmar; Taubert, Richard

   • Vol. 14: p38MAPK/MK2 signaling stimulates host cells autophagy pathways to restrict Salmonella infection.

     p. 1245443

     Suwandi, Abdulhadi; Menon, Manoj B.; Kotlyarov, Alexey; Grassl, Guntram A; Gaestel, Matthias
4. 2022

   • Vol. 13: Systematic pattern analyses of Vδ2+ TCRs reveal that shared "public" Vδ2+ γδ T cell clones are a consequence of rearrangement bias and a higher expansion status.

     Deng, Lihua; Harms, Anna; Ravens, Sarina; Prinz, Immo; Tan, Likai

   • Vol. 13: Phenotypic spectrum in recessive STING-associated vasculopathy with onset in infancy : Four novel cases and analysis of previously reported cases

     Wan, Rensheng; Fänder, Johannes; Zakaraia, Ia; Lee-Kirsch, Min Ae; Wolf, Christine; Lucas, Nadja; Olfe, Lisa Isabel; Hendrich, Corinna; Jonigk, Danny; Holzinger, Dirk; Steindor, Mathis; Schmidt, Gunnar; Claudia, Davenport; Klemann, Christian; Schwerk, Nicolaus; Griese, Matthias; Schlegelberger, Brigitte; Stehling, Florian; Happle, Christine; Auber, Bernd; Steinemann, Doris; Wetzke, Martin; von Hardenberg, Sandra

   • Vol. 13: In vitro systems to study inborn errors of immunity using human induced pluripotent stem cells.

     Nikolouli, Eirini; Reichstein, Janne; Hansen, Gesine; Lachmann, Nico

   • Vol. 13: Three Layers of Intestinal γδ T Cells Talk Different Languages With the Microbiota

     p. 849954

     Rampoldi, Francesca; Prinz, Immo

   • Vol. 13: Membrane-bound IL-2 improves the expansion, survival, and phenotype of CAR Tregs and confers resistance to calcineurin inhibitors.

     p. 1005582

     Kremer, Jakob; Henschel, Pierre; Simon, Daniel; Riet, Tobias; Falk, Christine; Hardtke-Wolenski, Matthias; Wedemeyer, Heiner; Noyan, Fatih; Jaeckel, Elmar
5. 2020

   • Vol. 11: Combating COVID-19 : MVA Vector Vaccines Applied to the Respiratory Tract as Promising Approach Toward Protective Immunity in the Lung

     p. 1959

     Förster, Reinhold; Fleige, Henrike; Sutter, Gerd

   • Vol. 11: Reversal of Immunity After Clearance of Chronic HCV Infection-All Reset?

     p. 571166

     Wedemeyer, Heiner; Khera, Tanvi; Strunz, Benedikt; Björkström, Niklas K.
6. 2019

   • Vol. 10: Hepatitis E Virus (HEV)-Specific T Cell Receptor Cross-Recognition: Implications for Immunotherapy.

     p. E2076

     Soon, Chai Fen; Zhang, Shihong; Suneetha, Pothakamuri Venkata; Antunes, Dinler Antunes; Manns, Michael Peter; Raha, Solaiman; Schultze-Florey, Christian R; Prinz, Immo; Wedemeyer, Heiner; Sällberg Chen, Margaret; Cornberg, Markus

   • Vol. 10: Autoimmunity (or Not) in Atopic Dermatitis.

     Roesner, Lennart M.; Werfel, Thomas