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High resolution flat-panel CT arthrography vs. MR arthrography of artificially created osteochondral defects in ex vivo upper ankle joints

Affiliation
Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany
Pöhler, Gesa H;
GND
1046304852
ORCID
0000-0001-5006-7260
Affiliation
Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany
Sonnow, Lena;
GND
1064719686
ORCID
0000-0002-6013-3417
Affiliation
Department of Orthopedic Surgery, Hannover Medical School at Diakovere Annastift, Hannover, Germany
Ettinger, Sarah;
GND
1243609850
Affiliation
Department of Orthopedic Surgery, Hannover Medical School at Diakovere Annastift, Hannover, Germany
Rahn, Alexandra;
GND
1245887009
ORCID
0000-0003-2715-0757
Affiliation
Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany
KlimeŇ°, Filip;
GND
128997052
ORCID
0000-0003-4645-6882
Affiliation
International Centrum for Hip, Knee and Foot Surgery, ATOS Clinic Heidelberg, Heidelberg, Germany
Becher, Christoph;
GND
130226947
ORCID
0000-0003-1681-9136
Affiliation
Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany
von Falck, Christian;
GND
1019957336
ORCID
0000-0002-6285-8403
Affiliation
Department of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany
Wacker, Frank;
GND
128721642
ORCID
0000-0003-0568-2074
Affiliation
Department of Orthopedic Surgery, Hannover Medical School at Diakovere Annastift, Hannover, Germany
Plaass, Christian

Purpose

High resolution flat-panel computed tomography arthrography (FPCT-A) and magnetic resonance arthrography (MR-A) are well suited to evaluate osteochondral lesions. The current study compares the performance of FPCT-A versus MR-A in an experimental setting.

Methods

Fourteen cadaveric ankles were prepared with artificial osteochondral defects of various sizes in four separate talar locations. After intra-articular contrast injection, FPCT-A and 3-T MR-A were acquired. Each defect was then filled with synthetic pallets. The resulting cast was used as reference. Two independent radiologists measured the dimensions of all defects with FPCT-A and MR-A. Intra-class correlation coefficients (ICC) were calculated. Data were compared using t-tests and Bland-Altman plots.

Results

The correlation for FPCT-A and cast was higher compared to MR-A and cast (ICC 0.876 vs. 0.799 for surface [length x width]; ICC 0.887 vs. 0.866 for depth, p<0.001). Mean differences between FPCT-A and cast measurements were -1.1 mm for length (p<0.001), -0.7 mm for width (p<0.001) and -0.4 mm for depth (p = 0.023). By MR-A, there were no significant differences for length and width compared to cast (p>0.05). Depth measurements were significantly smaller by MR-A (mean difference -1.1 mm, p<0.001). There was no bias between the different modalities.

Conclusions

Ex vivo FPCT-A and MR-A both deliver high diagnostic accuracy for the evaluation of osteochondral defects. FPCT-A was slightly more accurate than MR-A, which was most significant when measuring lesion depth.

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