Human CFTR deficient iPSC-macrophages reveal impaired functional and transcriptomic response upon Pseudomonas aeruginosa infection

Category

Published in:

Frontiers in immunology
Vol. 15 (2024)Art.-No.:1397886

Volume:

15

Date Issued:

2024

DOI:

10.3389/fimmu.2024.1397886

Language:

English

Type of Resource:

Text

Publisher:

Frontiers Media SA

Keywords:

cystic fibrosis; macrophages; iPSC; infection; Pseudomonas aeruginosa; lung immunity

DDC subject of DNB:

610 Medical sciences Medicine

Hosting institution:

Hospitals and Institutes, Klinik für Pädiatrische Pneumologie, Allergologie und Neonatologie

Hosting institution:

Central Facilities, LEBAO

Hosting institution:

Hospitals and Institutes, Department of Cardiothoracic, Transplantation and Vascular Surgery

Hosting institution:

Central Facilities, Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH)

Hosting institution:

Central Facilities, DZL: Lungenforschung

Hosting institution:

Central Facilities, REBIRTH

Hosting institution:

Hospitals and Institutes, Institute of Functional and Applied Anatomy

Hosting institution:

Central Facilities, Exzellenzcluster RESIST

publications:

Erschienen in: Front Immunol 2024;15:1397886 https://doi/org/10.3389/fimmu.2024.1397886

funding:

Veröffentlichung gefördert aus dem Publikationsfonds der MHH 2024.